Managing statin-related muscle problems
نویسندگان
چکیده
منابع مشابه
Statin-Related Muscle Toxicity
yperlipidemia is widely recognized as one of the major risk factors for coronary heart disease (CHD). Whereas therapeutic lifestyle changes are the first-line modality for reducing low-density lipoprotein (LDL) cholesterol, many patients also require medication to achieve cholesterol level goals. Primary and secondary prevention studies have demonstrated that adequate reduction of LDL cholester...
متن کاملElectrophysiologic and clinico-pathologic characteristics of statin-induced muscle injury
Objective(s):In this study, we aimed at evaluation of electrophysiological and histopathalogical characteristics of statin-induced muscle injury as well as clinical features of patients who develop this condition in terms of frequency and pattern of evolution. Materials and Methods: Forty patients (age 39-74 years) including 25 subjects with type 2 diabetes mellitus, 9 with cardiovascular disea...
متن کاملMuscle coenzyme Q10 level in statin-related myopathy.
BACKGROUND Statin drugs (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) reduce the level of cholesterol by inhibiting the synthesis of mevalonate, an intermediary in the cholesterol biosynthetic pathway. Use of statin drugs has been associated with a variety of skeletal muscle-related complaints. Coenzyme Q10 (CoQ10), a component of the mitochondrial respiratory chain, is also synt...
متن کاملStatin-related myotoxicity.
Statin therapy has a very important role in decreasing cardiovascular risk, and treatment non-compliance may therefore be a concern in high cardiovascular risk patients. Myotoxicity is a frequent side effect of statin therapy and one of the main causes of statin discontinuation, which limits effective treatment of patients at risk of or with cardiovascular disease. Because of the high proportio...
متن کاملelectrophysiologic and clinico-pathologic characteristics of statin-induced muscle injury
objective(s):in this study, we aimed at evaluation of electrophysiological and histopathalogical characteristics of statin-induced muscle injury as well as clinical features of patients who develop this condition in terms of frequency and pattern of evolution. materials and methods: forty patients (age 39-74 years) including 25 subjects with type 2 diabetes mellitus, 9 with cardiovascular disea...
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ژورنال
عنوان ژورنال: Journal of the Ceylon College of Physicians
سال: 2015
ISSN: 2448-9514,0379-802X
DOI: 10.4038/jccp.v45i1-2.7730